Decoding Glycine-Proline-Glycine: More Than Just Anti-Glycation—Its Multi-Faceted Skincare Benefits Offer a New Shield for Skin Health

In the realm of skincare ingredients, Glycyl-L-Histidyl-L-Lysine—commonly known as "Goose Peptide"—has gradually gained consumer recognition for its reputation as a "sugar-fighting powerhouse." Yet its benefits extend far beyond that label. Recent scientific research and real-world application cases have demonstrated Goose Peptide's remarkable efficacy in repairing the skin barrier, combating oxidative stress, and improving skin texture, making it a versatile "all-rounder" in safeguarding skin health—and further advancing the evolution of science-based skincare.

Feature 1: Precisely targets sugar buildup, breaking down the "culprit" behind dull, sallow skin.

As the most critical function of carnosine, its anti-glycation ability has been extensively validated. Glycation end-products (AGEs), which result from the skin’s glycation process, can lead to collagen loss and dullness in skin tone. However, carnosine tackles this challenge through a "dual mechanism." According to experimental data from a Beijing-based dermatological research center, carnosine can competitively bind to free sugars in the body, reducing AGEs formation by more than 30%. At the same time, it also boosts the activity of skin metabolism enzymes, accelerating the breakdown of already formed AGEs—and helping the skin gradually regain its radiance and clarity.

"I’ve always had slightly yellowish skin because I love sweet treats, but after using a cream containing goose peptide, not only has the yellow tone faded, but even the fine lines around my eyes have become less noticeable," said Ms. Liu, a 32-year-old consumer. This powerful "anti-glycation + anti-aging" synergy is making goose peptide the go-to skincare choice for night owls and dessert lovers alike.

Feature 2: Repair the skin barrier and boost the skin's "resilience."

In addition to its anti-glycation benefits, carnosine has also gained significant attention for its skin-barrier repairing properties. Modern-day individuals are frequently exposed to external stressors such as UV radiation, pollution, and lack of sleep, which can easily compromise the skin barrier, leading to issues like redness, sensitivity, and dryness. Fortunately, carnosine’s small molecular structure allows it to penetrate deep into the stratum corneum, helping to promote tighter alignment of keratinocytes while simultaneously stimulating the synthesis of natural moisturizing factors like ceramides and hyaluronic acid—thereby reinforcing a robust protective barrier for the skin.

Clinical observations from a medical beauty institution reveal that, after treatments like laser freckle removal and photorejuvenation, subjects who used repair products containing goose-skin peptide experienced a 40% reduction in the duration of skin redness and a 50% decrease in dryness and peeling. "Goose-skin peptide offers gentle yet highly effective repair properties, helping post-procedure skin quickly regain its healthy condition while minimizing sensitivity risks," said the director of the institution's dermatology department.
Feature 3: Antioxidant and anti-aging, slowing down the skin's aging process

As we age, oxidative damage to the skin intensifies, leading to common signs of aging such as fine lines, sagging, and reduced elasticity. Glycine-proline-hydroxyproline (Gly-Pro-Hyp), a key component, boasts strong antioxidant properties that help neutralize free radicals and minimize oxidative stress, thereby protecting skin cells from harm. Research conducted by a cosmetics research team at a Guangzhou-based university has revealed that Gly-Pro-Hyp can boost the activity of superoxide dismutase (SOD) in the skin while simultaneously lowering levels of lipid peroxidation products like MDA—both of which play crucial roles in effectively delaying skin aging.

In practical applications, many consumers have reported that long-term use of skincare products containing goose-skin peptide significantly improves skin firmness and effectively reduces the appearance of fine and dry lines. An international skincare brand’s newly launched goose-skin-peptide anti-aging serum has already climbed into the top three best-selling products in its category just six months after its market debut, clearly demonstrating consumers’ strong endorsement of its anti-aging benefits.

Feature 4: Balances oil and moisture levels, addressing a variety of skin concerns.

For those with oily-acne-prone or combination-oily skin, imbalances in water and oil levels are a major cause of acne and enlarged pores. Glycine-proline-hydroxyproline (Gly-Pro-Hyp), a key ingredient, helps regulate sebum gland activity, reducing excessive oil production while replenishing moisture to maintain the skin’s natural balance. Trial results for individuals with oily-acne-prone skin showed that after 4 weeks of using skincare products containing Gly-Pro-Hyp, participants experienced a 25% reduction in oil secretion, a 30% decrease in acne breakouts, and noticeably smoother, more refined-looking pores.
The market outlook is promising as goose-skin peptide emerges as the "new favorite" skincare ingredient.

Thanks to its multiple skincare benefits, Glycyrrhiza Glabra Peptide—commonly known as "goose peptide"—is quickly becoming the "new favorite" among leading skincare brands. Not only is it widely used in anti-glycation and anti-aging products, but it’s also gradually expanding into niche areas like repair and oil-control formulations. Industry insiders predict that in the coming years, the market for skincare products featuring goose peptide will continue to grow steadily, positioning it as one of the "mainstream ingredients" in the skincare ingredient landscape.

Experts advise consumers to consider their skin type and personal skincare needs when choosing skincare products containing oligopeptide-24. It’s important to pay attention to the concentration of oligopeptide-24 in the product, as well as the other ingredients it contains, to maximize its skincare benefits and achieve optimal results.