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Hyaluronic Acid for Cosmetic and Medical Applications


The Hyaluronic Acid from Hunan Joinband Biotech Co., Ltd. is an acidic glycosaminoglycan also known as hyaluronan. The product page gives the CAS number 9004-61-9, the molecular formula (C14H21NO11)n and the EINECS registration number 232-678-0. The purity and the packaging specification fields are left blank on the page, so the buyer should confirm them with the supplier.

Medical Uses

The product page describes hyaluronic acid as a biochemical drug with high clinical value. It is used in ophthalmic surgery such as intraocular lens implantation, corneal transplantation and glaucoma surgery. It is also used to treat arthritis and to accelerate wound healing. Those uses are regulated, and the buyer should confirm the grade, the documentation and the registration required for the destination market.

For a medical application, the buyer should ask for the certificate of analysis, the manufacturing process, the endotoxin and microbial limits, and the stability data. A cosmetic grade is not automatically suitable for an ophthalmic product. The supplier should state the grade and the test method for the ordered batch.

The molecular form and the molecular weight affect the viscosity and the behavior of the product. The product page does not list the molecular weight range or the concentration. The buyer should confirm those parameters for the intended formulation, because two HA products with the same CAS number can behave differently in a solution.

Cosmetic Uses

In cosmetics, the product page states that hyaluronic acid helps keep the skin hydrated, smooth, delicate, soft and elastic. It is described as providing anti-wrinkle and wrinkle-preventing effects and helping restore the skin's natural physiological functions. Those claims should be supported by the formula and the test data for the finished product.

A formulator can use HA in a serum, a cream, a mask or a cleanser. The use level and the molecular weight should be matched to the product type and the claim. A high molecular weight HA stays closer to the surface, while a lower molecular weight can penetrate more easily. The buyer should ask for the molecular weight range and the recommended use level.

The product is listed under cosmetic ingredients, together with pharmaceutical intermediates and food additives. The buyer should confirm which grade is quoted and whether the same grade can be used for both cosmetic and food applications. A food-grade product needs its own documentation.

Quality and Documentation

The buyer should ask for the certificate of analysis, the safety data sheet, the heavy metal and microbial test results, and the shelf life. For an export order, the supplier should also confirm the packing, the label and the documents required by the destination. A product with a blank purity field on the website should be specified in writing before the order.

The storage conditions should be confirmed. Hyaluronic acid is often supplied as a powder or a solution, and the two forms have different storage requirements. The buyer should ask for the recommended temperature, the humidity and the protection from light.

A sample is the practical way to check the appearance, the solubility and the viscosity. The buyer should test the sample in the actual formulation before the bulk order. The test record should be kept as the reference for the production batch.

Ordering Notes

The order should state the grade, the purity, the molecular weight range, the form, the packaging, the quantity and the documents required. The buyer should also confirm the lead time, the minimum order quantity and the payment terms.

Joinband can be contacted through the phone and email shown on the product page. The buyer should send the application, the required grade and the target market so that the supplier can recommend the product and the documentation.

The Hyaluronic Acid is one ingredient in a formulation, and the result depends on the grade, the molecular weight, the use level and the process. A clear specification and a sample test reduce the risk of a batch that does not fit the product.

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